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Synthesis and Antiproliferative Activity of C-3 Functionalized Isobenzofuran-1(3H)-ones

A series of thirteen C-3 functionalized isobenzofuran-1(3H)-ones (phtalides) was synthesized via condensation, aromatization, and acetylation reactions. NMR (one and two dimensional experiments), IR, and mass spectrometry analysis allowed confirmation of the identity of the synthesized compounds. Th...

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Detalles Bibliográficos
Autores principales: Teixeira, Róbson Ricardo, Bressan, Gustavo Costa, Pereira, Wagner Luiz, Ferreira, Joana Gasperazzo, de Oliveira, Fabrício Marques, Thomaz, Deborah Campos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270182/
https://www.ncbi.nlm.nih.gov/pubmed/23377131
http://dx.doi.org/10.3390/molecules18021881