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The Combination of Mitragynine and Morphine Prevents the Development of Morphine Tolerance in Mice

Mitragynine (MG) is the major active alkaloid found in Mitragyna speciosa Korth. In the present study, we investigated the enhancement of analgesic action of MG when combined with morphine and the effect of the combination on the development of tolerance towards morphine. Mice were administered intr...

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Detalles Bibliográficos
Autores principales: Fakurazi, Sharida, Rahman, Shamima Abdul, Hidayat, Mohamad Taufik, Ithnin, Hairuszah, Moklas, Mohamad Aris Mohd, Arulselvan, Palanisamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270191/
https://www.ncbi.nlm.nih.gov/pubmed/23292329
http://dx.doi.org/10.3390/molecules18010666