Cargando…

An Efficient Approach to the Synthesis of Highly Congested 9,10-Dihydrophenanthrene-2,4-dicarbonitriles and Their Biological Evaluation as Antimicrobial Agents

An efficient and novel method for the synthesis in moderate to good yield (72%–84%) of a series of 3-amino-1-substituted-9,10-dihydrophenanthrene-2,4-dicarbonitriles 1–5 via one-pot multi-component reactions of aldehydes, malononitrile, 1-tetralone and ammonium acetate has been delineated. Cyclocond...

Descripción completa

Detalles Bibliográficos
Autores principales: Faidallah, Hassan M., Al-Shaikh, Khalid M. A., Sobahi, Tariq R., Khan, Khalid A., Asiri, Abdullah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270192/
https://www.ncbi.nlm.nih.gov/pubmed/24352023
http://dx.doi.org/10.3390/molecules181215704