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Ultrasound-Promoted One-Pot, Four-Component Synthesis of Pyridin-2(1H)-One Derivatives

An efficient one-pot synthesis of 1,6-diamino-2-oxo-1,2,3,4-tetrahydro- pyridine-3,5-dicarbonitrile derivatives by four-component piperidine-catalyzed reactions of a ketone, malononitrile, ethyl cyanoacetate and hydrazine hydrate under ultrasound irradiation is described. This method provides severa...

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Detalles Bibliográficos
Autores principales: Yang, Jinming, Li, Qiang, Zhang, Juanjuan, Lin, Wei, Wang, Juxian, Wang, Yucheng, Huang, Zhibin, Shi, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270196/
https://www.ncbi.nlm.nih.gov/pubmed/24287988
http://dx.doi.org/10.3390/molecules181214519