Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides

5-Chloropyrazinamide (5-Cl-PZA) is an inhibitor of mycobacterial fatty acid synthase I with a broad spectrum of antimycobacterial activity in vitro. Some N-phenylpyrazine-2-carboxamides with different substituents on both the pyrazine and phenyl core possess significant in vitro activity against Myc...

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Detalles Bibliográficos
Autores principales: Zitko, Jan, Servusová, Barbora, Paterová, Pavla, Mandíková, Jana, Kubíček, Vladimír, Kučera, Radim, Hrabcová, Veronika, Kuneš, Jiří, Soukup, Ondřej, Doležal, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270209/
https://www.ncbi.nlm.nih.gov/pubmed/24317522
http://dx.doi.org/10.3390/molecules181214807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270209/
https://www.ncbi.nlm.nih.gov/pubmed/24317522
http://dx.doi.org/10.3390/molecules181214807

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