Silica-Supported Polyphosphoric Acid in the Synthesis of 4-Substituted Tetrahydroisoquinoline Derivatives

We report herein an application of an α-amidoalkylation reaction, as an alternative efficient synthesis of 4-aryl- and 4-methyl-1,2,3,4-tetrahydroisoquinoline derivatives. The amides required for this purpose would result from reaction of aminoacetaldehyde dimethylacetal with different substituted b...

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Detalles Bibliográficos
Autores principales: Manolov, Stanimir, Nikolova, Stoyanka, Ivanov, Iliyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270241/
https://www.ncbi.nlm.nih.gov/pubmed/23377130
http://dx.doi.org/10.3390/molecules18021869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270241/
https://www.ncbi.nlm.nih.gov/pubmed/23377130
http://dx.doi.org/10.3390/molecules18021869

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