Cargando…

Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S)-cis-khellactone Derivatives

An asymmetric synthesis of a series of novel 4-methyl-(3'S,4'S)-cis-khellactone derivatives 3a–o is reported for the first time. Their structures were confirmed by (1)H-NMR, (13)C-NMR and MS. Their cytotoxic activity was evaluated by the MTT assay against three selected human cancer cell l...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Luhui, Du, Xue, Hu, Mengnan, Yan, Chaoqun, Liang, Taigang, Li, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270253/
https://www.ncbi.nlm.nih.gov/pubmed/23567363
http://dx.doi.org/10.3390/molecules18044158