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Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S)-cis-khellactone Derivatives
An asymmetric synthesis of a series of novel 4-methyl-(3'S,4'S)-cis-khellactone derivatives 3a–o is reported for the first time. Their structures were confirmed by (1)H-NMR, (13)C-NMR and MS. Their cytotoxic activity was evaluated by the MTT assay against three selected human cancer cell l...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270253/ https://www.ncbi.nlm.nih.gov/pubmed/23567363 http://dx.doi.org/10.3390/molecules18044158 |