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Advances in Kinetic Isotope Effect Measurement Techniques for Enzyme Mechanism Study

Kinetic isotope effects (KIEs) are a very powerful tool for investigating enzyme mechanisms. Precision of measurement is the most important factor for KIE determinations, especially for small heavy atom KIEs. Internal competition is commonly used to measure small KIEs on V/K. Several methods, includ...

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Detalles Bibliográficos
Autores principales: Gu, Hong, Zhang, Shuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270257/
https://www.ncbi.nlm.nih.gov/pubmed/23917115
http://dx.doi.org/10.3390/molecules18089278