Diosgenone Synthesis, Anti-Malarial Activity and QSAR of Analogues of This Natural Product

Solanum nudum Dunal steroids have been reported as being antimalarial compounds; however, their concentration in plants is low, meaning that the species could be threatened by over-harvesting for this purpose. Swern oxidation was used for hemisynthesis of diosgenone (one of the most active steroidal...

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Detalles Bibliográficos
Autores principales: Pabón, Adriana, Escobar, Gustavo, Vargas, Esteban, Cruz, Víctor, Notario, Rafael, Blair, Silvia, Echeverri, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270258/
https://www.ncbi.nlm.nih.gov/pubmed/23493102
http://dx.doi.org/10.3390/molecules18033356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270258/
https://www.ncbi.nlm.nih.gov/pubmed/23493102
http://dx.doi.org/10.3390/molecules18033356

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