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Diosgenone Synthesis, Anti-Malarial Activity and QSAR of Analogues of This Natural Product
Solanum nudum Dunal steroids have been reported as being antimalarial compounds; however, their concentration in plants is low, meaning that the species could be threatened by over-harvesting for this purpose. Swern oxidation was used for hemisynthesis of diosgenone (one of the most active steroidal...
Autores principales: | Pabón, Adriana, Escobar, Gustavo, Vargas, Esteban, Cruz, Víctor, Notario, Rafael, Blair, Silvia, Echeverri, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270258/ https://www.ncbi.nlm.nih.gov/pubmed/23493102 http://dx.doi.org/10.3390/molecules18033356 |
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