A Facile Synthesis of Fully Protected meso-Diaminopimelic Acid (DAP) and Its Application to the Preparation of Lipophilic N-Acyl iE-DAP

Synthesis of beneficial protected meso-DAP 9 by cross metathesis of the Garner aldehyde-derived vinyl glycine 1b with protected allyl glycine 2 in the presence of Grubbs second-generation catalyst was performed. Preparation of lipophilic N-acyl iE-DAP as potent agonists of NOD 1-mediated immune resp...

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Detalles Bibliográficos
Autores principales: Saito, Yukako, Yoshimura, Yuichi, Wakamatsu, Hideaki, Takahata, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270281/
https://www.ncbi.nlm.nih.gov/pubmed/23325104
http://dx.doi.org/10.3390/molecules18011162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270281/
https://www.ncbi.nlm.nih.gov/pubmed/23325104
http://dx.doi.org/10.3390/molecules18011162

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