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Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin

A new series of betulin derivatives containing one or two pharmacophores bearing an acetylenic and carbonyl function at the C-3 and/or C-28 positions has been synthesized and characterized by (1)H- and (13)C-NMR, IR, MS and elemental analyses. The crystal structure of 28-O-propynoylbetulin was deter...

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Detalles Bibliográficos
Autores principales: Boryczka, Stanisław, Bębenek, Ewa, Wietrzyk, Joanna, Kempińska, Katarzyna, Jastrzębska, Maria, Kusz, Joachim, Nowak, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270304/
https://www.ncbi.nlm.nih.gov/pubmed/23595090
http://dx.doi.org/10.3390/molecules18044526