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Insights into Structure-Activity Relationships of Somatostatin Analogs Containing Mesitylalanine

The non-natural amino acid mesitylalanine (2,4,6-trimethyl-L-phenylalanine; Msa) has an electron-richer and a more conformationally restricted side-chain than that of its natural phenylalanine counterpart. Taking these properties into account, we have synthesized ten somatostatin analogs containing...

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Detalles Bibliográficos
Autores principales: Martín-Gago, Pablo, Aragón, Eric, Gomez-Caminals, Marc, Fernández-Carneado, Jimena, Ramón, Rosario, Martin-Malpartida, Pau, Verdaguer, Xavier, López-Ruiz, Pilar, Colás, Begoña, Cortes, María Alicia, Ponsati, Berta, Macias, Maria J., Riera, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270305/
https://www.ncbi.nlm.nih.gov/pubmed/24287991
http://dx.doi.org/10.3390/molecules181214564