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Automated Solid-Phase Radiofluorination Using Polymer-Supported Phosphazenes

The polymer supported phosphazene bases PS-P(2)(tBu) and the novel PS-P(2)(PEG) allowed for efficient extraction of [(18)F]F− from proton irradiated [(18)O]H(2)O and subsequent radiofluorination of a broad range of substrates directly on the resin. The highest radiochemical yields were obtained with...

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Detalles Bibliográficos
Autores principales: Mathiessen, Bente, Zhuravlev, Fedor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270316/
https://www.ncbi.nlm.nih.gov/pubmed/23999726
http://dx.doi.org/10.3390/molecules180910531