Technologies for the Synthesis of mRNA-Encoding Libraries and Discovery of Bioactive Natural Product-Inspired Non-Traditional Macrocyclic Peptides

In this review, we discuss emerging technologies for drug discovery, which yields novel molecular scaffolds based on natural product-inspired non-traditional peptides expressed using the translation machinery. Unlike natural products, these technologies allow for constructing mRNA-encoding libraries...

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Detalles Bibliográficos
Autores principales: Ito, Kenichiro, Passioura, Toby, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270345/
https://www.ncbi.nlm.nih.gov/pubmed/23507778
http://dx.doi.org/10.3390/molecules18033502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270345/
https://www.ncbi.nlm.nih.gov/pubmed/23507778
http://dx.doi.org/10.3390/molecules18033502

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