A Facile Synthesis of Functionalized Dispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction

An efficient synthesis of novel dispirooxindoles has been achieved through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5-benzylideneimidazolidine-2,4-dione. The improved proc...

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Detalles Bibliográficos
Autores principales: He, Jun, Ouyang, Guang, Yuan, Zhixiang, Tong, Rongsheng, Shi, Jianyou, Ouyang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270352/
https://www.ncbi.nlm.nih.gov/pubmed/23644979
http://dx.doi.org/10.3390/molecules18055142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270352/
https://www.ncbi.nlm.nih.gov/pubmed/23644979
http://dx.doi.org/10.3390/molecules18055142

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