The Effect of Molecular Crowding on the Stability of Human c-MYC Promoter Sequence I-Motif at Neutral pH

We have previously shown that c-MYC promoter sequences can form stable i-motifs in acidic solution (pH 4.5–5.5). In terms of drug targeting, the question is whether c-MYC promoter sequence i-motifs will exist in the nucleus at neutral pH. In this work, we have investigated the stability of a mutant...

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Detalles Bibliográficos
Autores principales: Cui, Jingjing, Waltman, Phillip, Le, Vu H., Lewis, Edwin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270392/
https://www.ncbi.nlm.nih.gov/pubmed/24132198
http://dx.doi.org/10.3390/molecules181012751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270392/
https://www.ncbi.nlm.nih.gov/pubmed/24132198
http://dx.doi.org/10.3390/molecules181012751

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