One-Pot Synthesis of Novel Chiral β-Amino Acid Derivatives by Enantioselective Mannich Reactions Catalyzed by Squaramide Cinchona Alkaloids

An efficient one-pot synthesis of novel β-amino acid derivatives containing a thiadiazole moiety was developed using a chiral squaramide cinchona alkaloid as organocatalyst. The reactions afforded chiral β-amino acid derivatives in moderate yields and with moderate to excellent enantioselectivities....

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Detalles Bibliográficos
Autores principales: Zhang, Kankan, Liang, Xueping, He, Ming, Wu, Jian, Zhang, Yuping, Xue, Wei, Jin, Linhong, Yang, Song, Hu, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270396/
https://www.ncbi.nlm.nih.gov/pubmed/23702920
http://dx.doi.org/10.3390/molecules18066142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270396/
https://www.ncbi.nlm.nih.gov/pubmed/23702920
http://dx.doi.org/10.3390/molecules18066142

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