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Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates

Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labeling strategy with click chemistry is now widely used...

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Detalles Bibliográficos
Autores principales: Yang, Yinliang, Yang, Xiaomeng, Verhelst, Steven H. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270401/
https://www.ncbi.nlm.nih.gov/pubmed/24126377
http://dx.doi.org/10.3390/molecules181012599

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