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Design, Synthesis and Cytotoxic Activities of Novel Aliphatic Amino-Substituted Flavonoids

A series of flavonoids 9a–f, 13b, 13d, 13e and 14a–f bearing diverse aliphatic amino moieties were designed, synthesized and evaluated for their cytotoxic activities against the ECA-109, A-549, HL-60, and PC-3 cancer cell lines. Most of the compounds exhibited moderate to good activities. The struct...

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Detalles Bibliográficos
Autores principales: Liu, Guannan, Ge, Zhen, Zhao, Mengdan, Zhou, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270462/
https://www.ncbi.nlm.nih.gov/pubmed/24232740
http://dx.doi.org/10.3390/molecules181114070