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Design, Synthesis and Cytotoxic Activities of Novel Aliphatic Amino-Substituted Flavonoids
A series of flavonoids 9a–f, 13b, 13d, 13e and 14a–f bearing diverse aliphatic amino moieties were designed, synthesized and evaluated for their cytotoxic activities against the ECA-109, A-549, HL-60, and PC-3 cancer cell lines. Most of the compounds exhibited moderate to good activities. The struct...
Autores principales: | Liu, Guannan, Ge, Zhen, Zhao, Mengdan, Zhou, Yifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270462/ https://www.ncbi.nlm.nih.gov/pubmed/24232740 http://dx.doi.org/10.3390/molecules181114070 |
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