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Development of a New Positron Emission Tomography Tracer for Targeting Tumor Angiogenesis: Synthesis, Small Animal Imaging, and Radiation Dosimetry

Angiogenesis plays a key role in cancer progression and correlates with disease aggressiveness and poor clinical outcomes. Affinity ligands discovered by screening phage display random peptide libraries can be engineered to molecularly target tumor blood vessels for noninvasive imaging and early det...

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Detalles Bibliográficos
Autores principales: Patterson, Cam, Frederick, C. Brandon, Yuan, Hong, Dyer, Laura A., Lockyer, Pamela, Lalush, David S., Veleva, Anka N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270467/
https://www.ncbi.nlm.nih.gov/pubmed/23676470
http://dx.doi.org/10.3390/molecules18055594