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Panduratin A, a Possible Inhibitor in Metastasized A549 Cells through Inhibition of NF-Kappa B Translocation and Chemoinvasion

In the present study, we investigated the effects of panduratin A (PA), isolated from Boesenbergia rotunda, on apoptosis and chemoinvasion in A549 human non-small cell lung cancer cells. Activation of the executioner procaspase-3 by PA was found to be dose-dependent. Caspase-3 activity was significa...

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Detalles Bibliográficos
Autores principales: Cheah, Shiau-Chuen, Lai, Siew-Li, Lee, Sui-Ting, Hadi, A. Hamid A., Mustafa, Mohd. Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270481/
https://www.ncbi.nlm.nih.gov/pubmed/23887718
http://dx.doi.org/10.3390/molecules18088764