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Chelator-Accelerated One-Pot ‘Click’ Labeling of Small Molecule Tracers with 2-[(18)F]Fluoroethyl Azide
2-[(18)F]Fluoroethyl azide ([(18)F]FEA) can readily be obtained by nucleophilic substitution of 2-azidoethyl-4-toluenesulfonate with [(18)F]fluoride (half-life 110 min), and has become widely used as a reagent for ‘click’ labeling of PET tracers. However, distillation of [(18)F]FEA is typically requ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270487/ https://www.ncbi.nlm.nih.gov/pubmed/23666002 http://dx.doi.org/10.3390/molecules18055335 |