Synthesis of a New ent-Cyclozonarone Angular Analog, and Comparison of Its Cytotoxicity and Apoptotic Effects with ent-Cyclozonarone

The synthesis of a newangular analog 11 of cyclozonarone was achieved via Diels-Alder reaction between a sesquiterpene-1,3-diene and 1,4-benzoquinone. The cytotoxic activity of ent-cyclozonarone [(+)-10] and the angular (−)-cyclozonarone analog 11 has been determined in three human cancer cell lines...

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Detalles Bibliográficos
Autores principales: Sobarzo, Natalia Quiñones, Venegas, Iván Montenegro, Sánchez, Cristian Salas, Catalán, Luis Espinoza, Rojas, Cristóbal Carrasco, Valdivia, Valentina Ulloa, García, Joan Villena, Fritis, Mauricio Cuellar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270499/
https://www.ncbi.nlm.nih.gov/pubmed/23669634
http://dx.doi.org/10.3390/molecules18055517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270499/
https://www.ncbi.nlm.nih.gov/pubmed/23669634
http://dx.doi.org/10.3390/molecules18055517

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