Helping Eve Overcome ADAM: G-Quadruplexes in the ADAM-15 Promoter as New Molecular Targets for Breast Cancer Therapeutics

ADAM-15, with known zymogen, secretase, and disintegrin activities, is a catalytically active member of the ADAM family normally expressed in early embryonic development and aberrantly expressed in various cancers, including breast, prostate and lung. ADAM-15 promotes extracellular shedding of E-cad...

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Detalles Bibliográficos
Autores principales: Brown, Robert V., Gaerig, Vanessa C., Simmons, Taesha, Brooks, Tracy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270510/
https://www.ncbi.nlm.nih.gov/pubmed/24317528
http://dx.doi.org/10.3390/molecules181215019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270510/
https://www.ncbi.nlm.nih.gov/pubmed/24317528
http://dx.doi.org/10.3390/molecules181215019

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