Cargando…

Design, Synthesis and Evaluation of N13-Substituted Evodiamine Derivatives against Human Cancer Cell Lines

Attempting to improve the anticancer activity and solubility of evodiamine in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) solutions, thirty-eight N13-substituted evodiamine derivatives were designed, synthesized and tested for antitumor activities against six kinds of human ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Senchuan, Chen, Zhiyong, Li, Shaoxue, Huang, Yanmin, Wan, Yiqian, Song, Huacan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270516/
https://www.ncbi.nlm.nih.gov/pubmed/24352027
http://dx.doi.org/10.3390/molecules181215750