Structural Characterization of de Novo Designed L(5)K(5)W Model Peptide Isomers with Potent Antimicrobial and Varied Hemolytic Activities

In an effort to develop short antimicrobial peptides with simple amino acid compositions, we generated a series of undecapeptide isomers having the L(5)K(5)W formula. Amino acid sequences were designed to be perfectly amphipathic when folded into a helical conformation by converging leucines onto on...

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Detalles Bibliográficos
Autores principales: Kim, Seo-Jin, Kim, Jae-Seok, Lee, Yoo-Sup, Sim, Dae-Won, Lee, Sung-Hee, Bahk, Young-Yil, Lee, Kwang-Ho, Kim, Eun-Hee, Park, Sung-Jean, Lee, Bong-Jin, Won, Hyung-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270530/
https://www.ncbi.nlm.nih.gov/pubmed/23344198
http://dx.doi.org/10.3390/molecules18010859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270530/
https://www.ncbi.nlm.nih.gov/pubmed/23344198
http://dx.doi.org/10.3390/molecules18010859

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