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Structural Characterization of de Novo Designed L(5)K(5)W Model Peptide Isomers with Potent Antimicrobial and Varied Hemolytic Activities
In an effort to develop short antimicrobial peptides with simple amino acid compositions, we generated a series of undecapeptide isomers having the L(5)K(5)W formula. Amino acid sequences were designed to be perfectly amphipathic when folded into a helical conformation by converging leucines onto on...
Autores principales: | Kim, Seo-Jin, Kim, Jae-Seok, Lee, Yoo-Sup, Sim, Dae-Won, Lee, Sung-Hee, Bahk, Young-Yil, Lee, Kwang-Ho, Kim, Eun-Hee, Park, Sung-Jean, Lee, Bong-Jin, Won, Hyung-Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270530/ https://www.ncbi.nlm.nih.gov/pubmed/23344198 http://dx.doi.org/10.3390/molecules18010859 |
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