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Apoptosis Sensitization by Euphorbia Factor L1 in ABCB1-Mediated Multidrug Resistant K562/ADR Cells

In this article, reversal activities of Euphorbia factor L1 (EFL1) against ABCB1-mediated multidrug resistance (MDR) and apoptosis sensitization in K562/ADR cells are reported. EFL1 decreased the IC(50) values of anticancer agents in K562/ADR cells over-expressing ABCB1. However, EFL1 did not affect...

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Detalles Bibliográficos
Autores principales: Zhang, Jian-Ye, Lin, Min-Ting, Yi, Tao, Tang, Yi-Na, Fan, Lan-Lan, He, Xi-Cheng, Zhao, Zhong-Zhen, Chen, Hu-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270536/
https://www.ncbi.nlm.nih.gov/pubmed/24135937
http://dx.doi.org/10.3390/molecules181012793