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Design, Synthesis and Trypanocidal Evaluation of Novel 1,2,4-Triazoles-3-thiones Derived from Natural Piperine

The work reported herein describes the synthesis and the assessment of the trypanocidal activity of thirteen new 1,2,4-triazole-3-thiones obtained from natural piperine, the main constituent of the dry fruits of Piper nigrum. It is part of a research program aiming to use abundant and easily availab...

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Detalles Bibliográficos
Autores principales: Franklim, Tatiany Nunes, Freire-de-Lima, Leonardo, de Nazareth Sá Diniz, Julliana, Previato, José Osvaldo, Castro, Rosane Nora, Mendonça-Previato, Lucia, de Lima, Marco Edilson Freire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270562/
https://www.ncbi.nlm.nih.gov/pubmed/23760033
http://dx.doi.org/10.3390/molecules18066366