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Synthesis and Protective Effect of New Ligustrazine-Benzoic Acid Derivatives against CoCl(2)-Induced Neurotoxicity in Differentiated PC12 Cells

A series of novel ligustrazine-benzoic acid derivatives were synthesized and evaluated for their protective effect against cobalt chloride-induced neurotoxicity in differentiated PC12 cells. Combining hematoxylin and eosin staining, we found compound that (3,5,6-trimethylpyrazin-2-yl)methyl 3-methox...

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Detalles Bibliográficos
Autores principales: Wang, Penglong, Zhang, Honggui, Chu, Fuhao, Xu, Xin, Lin, Jinxuan, Chen, Chunxiao, Li, Guoliang, Cheng, Yatao, Wang, Lin, Li, Qiang, Zhang, Yuzhong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270565/
https://www.ncbi.nlm.nih.gov/pubmed/24145795
http://dx.doi.org/10.3390/molecules181013027