Synthesis and Biological Activity of 6-Selenocaffeine: Potential Modulator of Chemotherapeutic Drugs in Breast Cancer Cells

We report the development of a new microwave-based synthetic methodology mediated by Woollins’ reagent that allowed an efficient conversion of caffeine into 6-selenocaffeine. A preliminary evaluation on the modulation of antioxidant activity upon selenation of caffeine, using the DPPH assay, indicat...

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Detalles Bibliográficos
Autores principales: Martins, Inês L., Miranda, Joana P., Oliveira, Nuno G., Fernandes, Ana S., Gonçalves, Sandrina, Antunes, Alexandra M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270583/
https://www.ncbi.nlm.nih.gov/pubmed/23698041
http://dx.doi.org/10.3390/molecules18055251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270583/
https://www.ncbi.nlm.nih.gov/pubmed/23698041
http://dx.doi.org/10.3390/molecules18055251

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