An Efficient Synthesis of Enantiopure (R)-heteroarylpyrimidine Analogs

An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-...

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Detalles Bibliográficos
Autores principales: Yang, Xiu-Yan, Xia, Guang-Qiang, Wang, Xiao-Kui, Zheng, Zhi-Bing, Zhao, Dong-Mei, Zhao, Guo-Ming, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270617/
https://www.ncbi.nlm.nih.gov/pubmed/24029747
http://dx.doi.org/10.3390/molecules180911144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270617/
https://www.ncbi.nlm.nih.gov/pubmed/24029747
http://dx.doi.org/10.3390/molecules180911144

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