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An Efficient Synthesis of Enantiopure (R)-heteroarylpyrimidine Analogs

An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-...

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Detalles Bibliográficos
Autores principales:	Yang, Xiu-Yan, Xia, Guang-Qiang, Wang, Xiao-Kui, Zheng, Zhi-Bing, Zhao, Dong-Mei, Zhao, Guo-Ming, Li, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270617/ https://www.ncbi.nlm.nih.gov/pubmed/24029747 http://dx.doi.org/10.3390/molecules180911144

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