Synthesis and Preliminary Biological Evaluations of 5′-Substituted Derivatives of Uridine as Glycosyltransferase Inhibitors

New derivatives of uridine which contain a β-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1–4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and were not active against Candida albicans and Aspergil...

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Detalles Bibliográficos
Autores principales: Paszkowska, Jadwiga, Kral, Katarzyna, Bieg, Tadeusz, Nawrot, Urszula, Szeja, Wiesław, Wandzik, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270623/
https://www.ncbi.nlm.nih.gov/pubmed/23884133
http://dx.doi.org/10.3390/molecules18078018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270623/
https://www.ncbi.nlm.nih.gov/pubmed/23884133
http://dx.doi.org/10.3390/molecules18078018

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