Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies

Using pregnenolone and 7-deoxycholic acid as starting materials, some 17-acetamidoandrostane and N,N-dimethyl-7-deoxycholic amide derivatives were synthesized. The cytotoxicity of the synthesized compounds was tested in vitro against two tumor cell lines: SGC 7901 (human gastric carcinoma) and Bel 7...

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Detalles Bibliográficos
Autores principales: Huang, Yanmin, Cui, Jianguo, Jia, Linyi, Gan, Chunfang, Song, Huacan, Zeng, Chun, Zhou, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270639/
https://www.ncbi.nlm.nih.gov/pubmed/23803715
http://dx.doi.org/10.3390/molecules18077436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270639/
https://www.ncbi.nlm.nih.gov/pubmed/23803715
http://dx.doi.org/10.3390/molecules18077436

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