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Mixed Antimony(V) Complexes with Different Sugars to Modulate the Oral Bioavailability of Pentavalent Antimonial Drugs

Previous studies have shown that the association of the drug meglumine antimoniate (MA) with β-cyclodextrin can improve its bioavailability by the oral route. In this work, ribose and maltose were investigated for their ability to form mixed or association complexes with MA, release MA and modulate...

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Detalles Bibliográficos
Autores principales: Ferreira, Weverson A., Islam, Arshad, Andrade, Aretha Priscilla S., Fernandes, Flaviana R., Frézard, Frédéric, Demicheli, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270655/
https://www.ncbi.nlm.nih.gov/pubmed/24786687
http://dx.doi.org/10.3390/molecules19055478