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Enantioselective Separation of Mirtazapine and Its Metabolites by Capillary Electrophoresis with Acetonitrile Field-Amplified Sample Stacking and Its Application

A simple, rapid and sensitive chiral capillary zone electrophoresis coupled with acetonitrile-field-amplified sample stacking method was developed that allows the simultaneous enantioselective separation of the mirtazapine, N-demethylmirtazapine, 8-hydroxymirtazapine and mirtazapine-N-oxide. The sep...

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Detalles Bibliográficos
Autores principales: Wen, Jun, Zhang, Wen-Ting, Cao, Wei-Qun, Li, Ji, Gao, Fang-Yuan, Yang, Nan, Fan, Guo-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270698/
https://www.ncbi.nlm.nih.gov/pubmed/24747648
http://dx.doi.org/10.3390/molecules19044907