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Small Molecule Tyrosine Kinase Inhibitors of ErbB2/HER2/Neu in the Treatment of Aggressive Breast Cancer

The human epidermal growth factor receptor 2 (HER2) is a member of the erbB class of tyrosine kinase receptors. These proteins are normally expressed at the surface of healthy cells and play critical roles in the signal transduction cascade in a myriad of biochemical pathways responsible for cell gr...

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Detalles Bibliográficos
Autores principales: Schroeder, Richard L., Stevens, Cheryl L., Sridhar, Jayalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270702/
https://www.ncbi.nlm.nih.gov/pubmed/25251190
http://dx.doi.org/10.3390/molecules190915196