Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

The cell division cycle 25 (CDC25) phosphatases include CDC25A, CDC25B and CDC25C. These three molecules are important regulators of several steps in the cell cycle, including the activation of various cyclin-dependent kinases (CDKs). CDC25s seem to have a role in the development of several human ma...

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Detalles Bibliográficos
Autores principales: Brenner, Annette K., Reikvam, Håkon, Lavecchia, Antonio, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270710/
https://www.ncbi.nlm.nih.gov/pubmed/25397735
http://dx.doi.org/10.3390/molecules191118414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270710/
https://www.ncbi.nlm.nih.gov/pubmed/25397735
http://dx.doi.org/10.3390/molecules191118414

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