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Inhibition and Biochemical Characterization of Methicillin-Resistant Staphylococcus aureus Shikimate Dehydrogenase: An in Silico and Kinetic Study

Methicillin-resistant Staphylococcus auerus (MRSA) strains are having a major impact worldwide, and due to their resistance to all β-lactams, an urgent need for new drugs is emerging. In this regard, the shikimate pathway is considered to be one of the metabolic features of bacteria and is absent in...

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Detalles Bibliográficos
Autores principales: Avitia-Domínguez, Claudia, Sierra-Campos, Erick, Salas-Pacheco, José Manuel, Nájera, Hugo, Rojo-Domínguez, Arturo, Cisneros-Martínez, Jorge, Téllez-Valencia, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270726/
https://www.ncbi.nlm.nih.gov/pubmed/24727420
http://dx.doi.org/10.3390/molecules19044491