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Synthesis and Characterization of Impurities of Barnidipine Hydrochloride, an Antihypertensive Drug Substance

Barnidipine hydrochloride is a long term dihydropyridine calcium channel blocker used for the treatment of hypertension. During the process development of barnidipine hydrochloride, four barnidipine impurities were detected by high-performance liquid chromatography (HPLC) with an ordinary column (Ag...

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Detalles Bibliográficos
Autores principales: Cheng, Zhi-Gang, Dai, Xu-Yong, Li, Li-Wei, Wan, Qiong, Ma, Xiang, Xiang, Guang-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270734/
https://www.ncbi.nlm.nih.gov/pubmed/24451253
http://dx.doi.org/10.3390/molecules19011344