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Synthesis of Tetrahydrohonokiol Derivates and Their Evaluation for Cytotoxic Activity against CCRF-CEM Leukemia, U251 Glioblastoma and HCT-116 Colon Cancer Cells

Biphenyl neolignans such as honokiol and magnolol, which are the major active constituents of the Asian medicinal plant Magnolia officinalis, are known to exert a multitude of pharmacological and biological activities. Among these, cytotoxic and tumor growth inhibitory activity against various tumou...

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Detalles Bibliográficos
Autores principales: Bernaskova, Marketa, Kretschmer, Nadine, Schuehly, Wolfgang, Huefner, Antje, Weis, Robert, Bauer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270748/
https://www.ncbi.nlm.nih.gov/pubmed/24448063
http://dx.doi.org/10.3390/molecules19011223