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K(2)CO(3)-Mediated Synthesis of Functionalised 4-Substituted-2-amino-3-cyano-4H-chromenes via Michael-Cyclization Reactions

An efficient approach for the synthesis of functionalized 4-substituted-2-amino-3-cyano-4H-chromenes moderate to high yields (up to 98%) has been achieved via a tandem K(2)CO(3 )catalyzed conjugate addition-cyclization reaction of malononitrile and a range of Knoevenagel adducts previously formed fr...

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Detalles Bibliográficos
Autores principales: He, Yanyang, Hu, Rong, Tong, Rongsheng, Li, Fengqiong, Shi, Jianyou, Zhang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270755/
https://www.ncbi.nlm.nih.gov/pubmed/25429557
http://dx.doi.org/10.3390/molecules191219253