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Investigation of the Flexibility of Protein Kinases Implicated in the Pathology of Alzheimer’s Disease
The pathological characteristics of Alzheimer’s Disease (AD) have been linked to the activity of three particular kinases—Glycogen Synthase Kinase 3β (GSK3β), Cyclin-Dependent Kinase 5 (CDK5) and Extracellular-signal Regulated Kinase 2 (ERK2). As a consequence, the design of selective, potent and dr...
Autores principales: | Mazanetz, Michael P., Laughton, Charles A., Fischer, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270768/ https://www.ncbi.nlm.nih.gov/pubmed/24983862 http://dx.doi.org/10.3390/molecules19079134 |
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