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Icariin Is A PPARα Activator Inducing Lipid Metabolic Gene Expression in Mice

Icariin is effective in the treatment of hyperlipidemia. To understand the effect of icariin on lipid metabolism, effects of icariin on PPARα and its target genes were investigated. Mice were treated orally with icariin at doses of 0, 100, 200, and 400 mg/kg, or clofibrate (500 mg/kg) for five days....

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Detalles Bibliográficos
Autores principales: Lu, Yuan-Fu, Xu, Yun-Yan, Jin, Feng, Wu, Qin, Shi, Jing-Shan, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270773/
https://www.ncbi.nlm.nih.gov/pubmed/25383754
http://dx.doi.org/10.3390/molecules191118179