Cargando…
Icariin Is A PPARα Activator Inducing Lipid Metabolic Gene Expression in Mice
Icariin is effective in the treatment of hyperlipidemia. To understand the effect of icariin on lipid metabolism, effects of icariin on PPARα and its target genes were investigated. Mice were treated orally with icariin at doses of 0, 100, 200, and 400 mg/kg, or clofibrate (500 mg/kg) for five days....
Autores principales: | Lu, Yuan-Fu, Xu, Yun-Yan, Jin, Feng, Wu, Qin, Shi, Jing-Shan, Liu, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270773/ https://www.ncbi.nlm.nih.gov/pubmed/25383754 http://dx.doi.org/10.3390/molecules191118179 |
Ejemplares similares
-
PPARα is essential for retinal lipid metabolism and neuronal survival
por: Pearsall, Elizabeth A., et al.
Publicado: (2017) -
Wedelolactone Regulates Lipid Metabolism and Improves Hepatic Steatosis Partly by AMPK Activation and Up-Regulation of Expression of PPARα/LPL and LDLR
por: Zhao, Yun, et al.
Publicado: (2015) -
The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism()()
por: Huang, Jianfeng, et al.
Publicado: (2013) -
MDG-1, a Potential Regulator of PPARα and PPARγ, Ameliorates Dyslipidemia in Mice
por: Wang, Xu, et al.
Publicado: (2017) -
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice
por: Yan, Fei, et al.
Publicado: (2022)