Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins

A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated for their cytotoxic activity with respect to...

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Detalles Bibliográficos
Autores principales: Lipeeva, Alla V., Shults, Elvira E., Shakirov, Makhmut M., Pokrovsky, Mikhail A., Pokrovsky, Andrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270788/
https://www.ncbi.nlm.nih.gov/pubmed/24962392
http://dx.doi.org/10.3390/molecules19067881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270788/
https://www.ncbi.nlm.nih.gov/pubmed/24962392
http://dx.doi.org/10.3390/molecules19067881

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