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Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins
A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated for their cytotoxic activity with respect to...
Autores principales: | Lipeeva, Alla V., Shults, Elvira E., Shakirov, Makhmut M., Pokrovsky, Mikhail A., Pokrovsky, Andrey G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270788/ https://www.ncbi.nlm.nih.gov/pubmed/24962392 http://dx.doi.org/10.3390/molecules19067881 |
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